Study Title

Positron-Emission Tomography Detection of Sodium-Glucose Transport for Early Diagnosis of Lung Cancer

Study Details

Description:

The phase I/II trial assess the safety and efficacy of a new positron emission tomography (PET) test for early diagnosis of lung cancer. This study uses PET and Me-4FDG new glucose tracer (alpha-methyl-4-deoxy-4-[(18)F]fluoro-D-glucopyranoside) designed specifically to determine glucose update into cells in the body. PET is a non-invasive imaging method used to detect cancer in patient. Me4FDG is a radioactive glucose tracer used in PET to locate cells in the body taking up glucose by SGLT2. SLGT2 is a sodium glucose transport protein that accumulates glucose in some cells, e.g. kidney cells and tumors. This study may help researcher determine how effective PET with ME4FDG tracer works in detecting lung cancer.

Sponsor:

Jonsson Comprehensive Cancer Center (UCLA)

Inclusion
  • Lung nodules considered to be clinically benign
  • Age > 18 years
  • Lung nodule >= 1 cm visualized by CT imaging
  • Pathologically confirmed lung adenocarcinoma.
Exclusion
  • Current treatment with SGLT2 inhibitors or metformin
  • Diagnosis of diabetes
  • Pregnancy

Patient Education

Patient Education Not Yet Provided

Publications

Publications Not Yet Provided

Locations

Not yet provided.

XCancer

© 2021 XCancer Software LLC

Contact XCancer: 402-991-8468