Study Title

advancedacceleratorapplications

A Phase I/IIa Open-label, Multi-center Study to Evaluate the Safety, Tolerability, Whole-body Distribution, Radiation Dosimetry and Anti-tumor Activity of [177Lu]-NeoB Administered in Patients With Advanced Solid Tumors Known to Overexpress Gastrin-releasing Peptide Receptor (GRPR)

Study Details

Description:

The purpose of this first-in-human (FIH) study of [177Lu]-NeoB is to characterize the safety, tolerability, pharmacokinetics (PK) as well as the distribution and radiation dosimetry, and anti-tumor activity of [177Lu]-NeoB in patients with advanced solid tumors known to overexpress GRPR and with [68Ga]-NeoB lesion uptake.

Contacts:

Novartis Pharmaceuticals

novartis.email@novartis.com

1-888-669-6682

Patient Education

Patient Education Not Yet Provided

Publications

Publications Not Yet Provided




Stanford University Medical Center

Stanford, California 94305, United States


Lifespan Cancer Institute

Providence, Rhode Island 02903, United States


Duke University

Durham, North Carolina 27710, United States


Johns Hopkins University

Baltimore, Maryland 21287, United States


Austria

France

Germany

Spain

United Kingdom

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