Study Title

Phase 3 Trial of 177Lu-PSMA I&T versus Hormone Therapy in Patients with metastatic Castration-Resistant Prostate Cancer (mCRPC)

Study Details

Description:

A Multi-Center, Open-Label, Randomized Phase 3 Trial Comparing the Safety and Efficacy of 177Lu-PSMA I&T versus Hormone Therapy in Patients with Metastatic Castration-Resistant Prostate Cancer.

Sponsor:

Curium

Contacts:

Darcy Denner, Ph.D. (Clinical Trial Director)

darcy.denner@curiumpharma.com

Government Study Link:

NCT05204927 - Click here to see study on

ClinicalTrials.gov

Inclusion

Males, 18 years or older
Positive PSMA PET scan
Proven metastatic castration-resistant prostate cancer

Exclusion

Previous treatment with chemotherapy in the castration-resistant setting
Previous treatment with more than one ARAT
Previous treatment with other radioligand therapy

Patient Education

Publications

Publications Not Yet Provided

Locations

United States

XCancer - Omaha

17607 Gold Plaza, Omaha, Nebraska 68130, United States

This badge indicates the Principal Investigator has a proven record of excellence in the advancement of Theranostics.

Principal Investigator:

Luke T. Nordquist, MD

SUNY Upstate Medical Center

Syracuse, New York, United States

Arizona Institute of Urology, PPLC

Tucson, Arizona 85704, United States

Biogenix Molecular LLC

Miami, Florida 33165, United States

Florida Urology Partners, LLP

Tampa, Florida 33607, United States

VA Portland Health Care System

Portland, Oregon 97239, United States

Hightower Clinical

Oklahoma City, Oklahoma 73102, United States

Houston Metro Urology

Houston, Texas 77027, United States

Columbia University Medical Center - Herbert Irving Pavilion

New York, New York, United States

M Health Fairview Ridges Cancer Clinic

Burnsville, Minnesota 55337, United States

Central Ohio Urology Group

Columbus, Ohio 43230, United States

BAMF Health

Grand Rapids, Michigan 49503, United States

Northwestern Memorial Hospital

Chicago, Illinois 60611, United States

NorthShore University HealthSystem-Evanston Hospital

Evanston, Illinois 60201, United States

GenesisCare USA

Boca Raton, Florida 33431, United States

OHSU - Center for health and healing

Portland, Oregon 97239, United States

MidLantic Urology

Bala Cynwyd, Pennsylvania 19004, United States

Providence Saint John's Health Center

Santa Monica, California 90404, United States

Michigan Institute of Urology

Troy, Michigan 48084, United States

Icahn School of Medicine at Mount Sinai

New York, New York, New York 10024, United States

Oncology Hematology West, PC dba Nebraska Cancer Specialists

Omaha, Nebraska 68130, United States

Hoag Memorial Hospital Presbyterian

Newport Beach, California, United States

Rutgers Cancer Institute of New Jersey

New Brunswick, New Jersey, United States

University of California, San Francisco

San Francisco, California 94158, United States

Providence Medical Foundation

Fullerton, California 92835, United States

Urology San Antonio

San Antonio, Texas 78229, United States

Kaiser Permanente Gaithersburg Medical Center

Gaithersburg, Maryland 20879, United States

SSM Saint Louis University Hospital

St. Louis, Missouri 63104, United States

Orlando Health Cancer Institute

Orlando, Florida 32806, United States

Center for Clinical Theranostics Research, Washington University

St. Louis, Missouri 63110, United States

Long Beach Memorial Center

Long Beach, California 90806, United States

San Francisco VA Health Care System

San Francisco, California 94121, United States

Henry Ford Hospital

Detroit, Michigan 48202, United States

France

CHU Nimes

Nîmes, Gard, France

Hôpital de Brabois -CHU

Nancy, Meurthe-et-Moselle, France

Institut de Cancérologie de l'Ouest (ICO) St Herblain

Nantes, Loire-Atlantique, France

Institute Paoli-Calmettes

Marseille, Bouches-du-Rhône, France

CHU Brest

Brest, Finistère, France

ICANS

Strasbourg, Bas-Rhin, France

Jean Perrin Comprehensive Cancer Center

Clermont-Ferrand, Puy-de-Dôme, France

InstitutClaudius Regaud-IUCT-O

Toulouse, Haute-Garonne, France

Italy

ASST Grande Ospedale Metropolitano Niguarda

Milano, Milan, Italy

Istituto Europeo di Oncologia (IEO) -IRCCS

Milano, Milan, Italy

University Clinic Bologna

Bologna, Bologna, Italy

Spain

Fundación Jiménez Díaz

Madrid, Madrid, Spain

Hospital Universitario HM Sanchinarro

Madrid, Madrid, Spain

Hospital Regional Universitario de Malaga

Málaga, Málaga, Spain

University Hospital of Salamanca

Salamanca, Salamanca, Spain