Study Title

Evaluation of the Diagnostic, Prognostic and Follow-up Potential of 4,16α-[16α-18F]Difluoro-11β-methoxyestradiol (4FMFES) PET Imaging for Estrogen Receptor Positive Advanced Breast Cancers

Study Details

Description:

This proposed project will focus on 3 specific aims: Compare and complement 4FMFES-PET with FDG-PET and conventional imaging modalities, and evaluate how they improved prognosis and staging of ER+ advanced breast cancer patients; Correlate 4FMFES/FDG uptake and staging with pathological data (histology, receptor status, grade), including distal biopsy metastases sampling; Correlate 4FMFES/FDG uptake and staging with longitudinal outcomes (treatment response, progression-free survival, time-to-relapse) to determine which cohort of patient benefit most from 4FMFES.

Sponsor:

Centre de recherche du Centre hospitalier universitaire de Sherbrooke

Contacts:

Michel Paquette, PhD (Principal Investigator)

michel.paquette@usherbrooke.ca

819-346-1110 ext 11-982

Stéphanie Dubreuil

stephanie.dubreuil2@usherbrooke.ca

819-346-1110 ext 16617

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